Sho-Ichi Yamagishi Selected Research

Blood Glucose (Blood Sugar)

1/2021	DNA aptamer raised against receptor for advanced glycation end products suppresses renal tubular damage and improves insulin resistance in diabetic mice.
1/2020	Oral administration of spa-derived green alga improves insulin resistance in overweight subjects: Mechanistic insights from fructose-fed rats.
1/2019	Role of Advanced Glycation Endproduct (AGE)-Receptor for Advanced Glycation Endproduct (RAGE) Axis in Cardiovascular Disease and Its Therapeutic Intervention.
10/2016	Protective role of sulphoraphane against vascular complications in diabetes.
1/2015	DNA Aptamer Raised against Advanced Glycation End Products Prevents Abnormalities in Electroretinograms of Experimental Diabetic Retinopathy.
3/2010	Advanced glycation end products, oxidative stress and diabetic nephropathy.

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Sho-Ichi Yamagishi Research Topics

Disease

22	Cardiovascular Diseases (Cardiovascular Disease) 12/2020 - 06/2007
15	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2018 - 04/2002
14	Diabetic Nephropathies (Diabetic Nephropathy) 01/2021 - 01/2008
13	Atherosclerosis 04/2021 - 06/2005
12	Type 2 Diabetes Mellitus (MODY) 09/2021 - 01/2009
12	Insulin Resistance 01/2021 - 12/2006
11	Neoplasms (Cancer) 08/2021 - 04/2004
10	Inflammation (Inflammations) 01/2020 - 10/2011
9	Body Weight (Weight, Body) 01/2022 - 12/2006
9	Diabetic Angiopathies (Diabetic Angiopathy) 10/2016 - 01/2004
8	Fibrosis (Cirrhosis) 05/2022 - 02/2003
7	Chronic Renal Insufficiency 10/2020 - 06/2007
6	Melanoma (Melanoma, Malignant) 01/2021 - 04/2004
6	Hyperglycemia 07/2020 - 07/2007
6	Albuminuria 04/2020 - 01/2014
5	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2022 - 07/2007
5	Neoplasm Metastasis (Metastasis) 01/2021 - 04/2015
5	Diabetes Complications 01/2018 - 01/2004
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2014 - 05/2005
4	Atherosclerotic Plaque (Atheroma) 05/2020 - 10/2011
4	Chronic Kidney Failure (Chronic Renal Failure) 09/2017 - 10/2006
3	Glucose Intolerance 01/2020 - 10/2011
3	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 09/2004
3	Uveitis 12/2014 - 02/2007
2	Cardiomegaly (Heart Hypertrophy) 05/2022 - 03/2021
2	Frailty 12/2021 - 10/2020
2	Hypertension (High Blood Pressure) 07/2020 - 08/2007
2	Dyslipidemias (Dyslipidemia) 07/2020 - 01/2010
2	Obesity 02/2020 - 12/2016
2	Vascular Calcification 01/2020 - 01/2019
2	Carotid Artery Diseases 01/2020 - 10/2011
2	Bone Fractures (Bone Fracture) 11/2019 - 01/2019
2	Vascular Remodeling 10/2019 - 01/2016
2	Atrial Fibrillation 01/2019 - 01/2019
2	Vascular System Injuries 01/2018 - 01/2010
2	Pathologic Neovascularization 01/2018 - 11/2013
2	Osteoporosis 01/2018 - 04/2015
2	Anemia 09/2017 - 01/2016
2	Schizophrenia (Dementia Praecox) 01/2017 - 01/2017
2	Dehydration (Water Stress) 01/2016 - 10/2015

Drug/Important Bio-Agent (IBA)

54	Advanced Glycation End ProductsIBA 08/2021 - 02/2003
28	pigment epithelium-derived factorIBA 08/2021 - 04/2004
16	Proteins (Proteins, Gene)FDA Link 05/2022 - 04/2004
14	Glucose (Dextrose)FDA LinkGeneric 09/2021 - 05/2005
9	Receptor for Advanced Glycation End ProductsIBA 01/2021 - 11/2005
8	GlyceraldehydeIBA 12/2021 - 09/2004
8	Nucleotide AptamersIBA 01/2021 - 01/2015
8	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 09/2017 - 06/2007
7	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2021 - 04/2004
7	Insulin (Novolin)FDA Link 01/2020 - 12/2006
7	Biomarkers (Surrogate Marker)IBA 01/2017 - 07/2010
6	NADPH Oxidases (NAD(P)H oxidase)IBA 08/2021 - 06/2005
6	Blood Glucose (Blood Sugar)IBA 01/2021 - 03/2010
5	Hemoglobins (Hemoglobin)IBA 03/2020 - 10/2011
5	HDL CholesterolIBA 01/2020 - 05/2005
5	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2020 - 06/2007
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2014 - 06/2007
5	Triglycerides (Triacylglycerol)IBA 02/2012 - 05/2005
5	Angiotensin IIIBA 08/2007 - 06/2005
4	CreatinineIBA 01/2021 - 02/2012
4	CholesterolIBA 07/2020 - 01/2010
4	Sodium-Glucose Transport ProteinsIBA 04/2020 - 11/2016
4	Uric Acid (Urate)IBA 01/2019 - 06/2006
4	Telmisartan (Micardis)FDA Link 05/2016 - 11/2005
4	Retinaldehyde (Retinal)IBA 09/2014 - 01/2005
3	EnzymesIBA 11/2022 - 05/2005
3	Messenger RNA (mRNA)IBA 05/2022 - 01/2004
3	pentosidineIBA 12/2021 - 09/2011
3	Dipeptidyl-Peptidase IV InhibitorsIBA 09/2021 - 02/2020
3	Glucagon (Glukagon)FDA Link 01/2021 - 12/2019
3	AlbuminsIBA 03/2020 - 04/2009
3	Hypoglycemic Agents (Hypoglycemics)IBA 02/2020 - 10/2011
3	SugarsIBA 10/2018 - 01/2008
3	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 11/2013
3	Cell Surface ReceptorsIBA 01/2018 - 01/2004
3	sulforaphaneIBA 01/2018 - 09/2014
3	Nitric Oxide Synthase (NO Synthase)IBA 02/2014 - 04/2009
2	ImmunosorbentsIBA 11/2022 - 12/2021
2	1,5- anhydro- 1- (5- (4- ethoxybenzyl)- 2- methoxy- 4- methylphenyl)- 1- thioglucitolIBA 05/2022 - 10/2019
2	SodiumIBA 01/2022 - 02/2018
2	Peptides (Polypeptides)IBA 03/2021 - 02/2014
2	HMGB1 Protein (HMG1)IBA 01/2021 - 12/2011
2	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2021 - 10/2019
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 12/2011
2	Streptozocin (Streptozotocin)FDA Link 07/2020 - 01/2017
2	AdiponectinIBA 01/2020 - 12/2016
2	Pioglitazone (Actos)FDA Link 01/2020 - 10/2011
2	FructoseIBA 01/2020 - 12/2016
2	AdipokinesIBA 10/2019 - 04/2015
2	6- ((4- ethylphenyl)methyl)- 3',4',5',6'- tetrahydro- 6'- (hydroxymethyl)spiro(isobenzofuran- 1(3H),2'- (2H)pyran)- 3',4',5'- triolIBA 01/2019 - 11/2016
2	glimepiride (Amarel)FDA LinkGeneric 01/2019 - 10/2011
2	LigandsIBA 10/2018 - 01/2004
2	Erythropoietin FDA Link 09/2017 - 01/2016
2	HematinicsIBA 09/2017 - 01/2016
2	A-factor (Streptomyces)IBA 12/2016 - 01/2004
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2016 - 01/2010

Therapy/Procedure

9	Therapeutics 03/2021 - 07/2007
6	Renal Dialysis (Hemodialysis) 01/2016 - 01/2008
2	Oral Administration 01/2020 - 12/2014
2	Glycemic Control 01/2019 - 01/2008